bs-76730C

DATASHEET

Formulation Powder

Storage: Stable for 2 years after receipt when stored at +4°C.

Product Information:

CAS Number: 29106-49-8

Molecular formula: C30H26O12

Molecular weight: 578.52

Purity: >90% (HPLC)

Appearance: Light beige/brown to beige/brown powder.

Solubility: Soluble in DMSO, ethanol, DMF (all 30mg/ml) or water (10mg/ml).

InChiKey: XFZJEEAOWLFHDH-NFJBMHMQSA-N

SMILES: O[C@@H]1[C@@H](C2=C3C(C[C@@H](O)[C@@H](C4=CC(O)=C(O)C=C4)O3)=C(O)C=C2O)C5=C(O)C=C(O)C=C5O[C@@H]1C6=CC(O)=C(O)C=C6

SMILES: O[C@@H]1CC2=C(O[C@@H]1C1=CC=C(O)C(O)=C1)C([C@@H]1[C@@H](O)[C@H](OC3=C1C(O)=CC(O)=C3)C1=CC(O)=C(O)C=C1)=C(O)C=C2O

Description:

Procyanidin B2, one of the most representative naturally occurring edible pigments, is usually isolated from the seeds, fruits and leaves of lots of common plants, such as grapes or apples. Procyanidin B2 has numerous bioactivities, including anti-inflammatory, anti-oxidative stress, neuroprotective, lipid metabolism regulating, wound healing, anti-diabetic, metabolic syndrome regulating, anti-atherosclerotic, anti-adipogenesis, anti-viral and anti-cancer properties. Procyanidin B2 targets and mediates several signaling pathways like NF-kappaB, MAPK, PI3K/Akt, NLRP3, apoptotic axis, VEGF/VEGFR2, PPARgamma and Nrf-2/HO-1. Procyanidin B2 possesses the potential to treat/prevent a wide range of human diseases, such as diabetes mellitus, diabetic complications, atherosclerosis, cancers and non-alcoholic fatty liver disease.