DATASHEET
Formulation
Powder
Storage:
Stable for 2 years after receipt when stored at RT.
Product Information:
CAS Number: 56-54-2
Molecular formula: C20H24N2O2
Molecular weight: 324.42
Purity: >99% (Titr.)
Appearance: White to faint yellow powder.
Solubility: Soluble in DMSO (20mg/ml) or ethanol (5mg/ml).
InChiKey: LOUPRKONTZGTKE-LHHVKLHASA-N
SMILES: O[C@@H](C1=C(C=C(OC)C=C2)C2=NC=C1)[C@]3([H])[N@](C[C@@H]4C=C)CC[C@@]4([H])C3
Description:
Quinidine is a dextrorotatory stereoisomer of Quinine with anti-malarial, anti-arrhythmic (class 1A), anti-inflammatory, anti-cancer and anti-viral properties. Quinidine acts as a blocker of voltage-gated sodium channels. Inhibition of the Nav1.5 channel is specifically involved in its anti-arrhythmic effects as a class I anti-arrhythmic agent. Quinidine also blocks certain voltage-gated potassium channels (e.g. Kv1.4, Kv4.2, hERG, among others), acts as an anti-muscarinic. Quinidine blocks alpha1-adrenoceptors (alpha1ARs) and is an inhibitor of cytochrome P450 and acetylcholinesterase.