DATASHEET
Formulation
Powder
Storage:
Stable for 2 years after receipt when stored at RT.
Product Information:
CAS Number: 136-47-0
Molecular formula: C15H24N2O2 . HCl
Molecular weight: 264.4 . 36.5
Purity: >99% (TLC)
Appearance: White to off-white powder.
Solubility: Soluble in water (40mg/ml), DMSO (40mg/ml) or ethanol (20mg/ml).
InChiKey: PPWHTZKZQNXVAE-UHFFFAOYSA-N
SMILES: CCCCNC1=CC=C(C(OCCN(C)C)=O)C=C1.Cl
SMILES: Cl.CCCCNC1=CC=C(C=C1)C(=O)OCCN(C)C
Description:
Tetracaine is a potent local anaesthetic and a channel function allosteric inhibitor that blocks voltage-sensitive release of Ca2+ from sarcoplasmic reticulum. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely. inhibitor of voltage-gated sodium channels such as NaV1.4 and NaV1.8. Shown also to reversibly block nicotinic acetylcholine (ACh) receptors (nAChRs).