DATASHEET
Formulation
Powder
Storage:
Stable for 2 years after receipt when stored at -20°C.
Product Information:
CAS Number: 94-24-6
Molecular formula: C15H24N2O
Molecular weight: 264.36
Purity: >98% (TLC)
Appearance: White to off-white powder.
Solubility: Soluble in DMSO or methanol. Almost insoluble in water.
InChiKey: GKCBAIGFKIBETG-UHFFFAOYSA-N
SMILES: CCCCNC1=CC=C(C(OCCN(C)C)=O)C=C1
SMILES: CCCCNC1=CC=C(C=C1)C(=O)OCCN(C)C
Description:
Tetracaine is a potent local anaesthetic and a channel function allosteric inhibitor that blocks voltage-sensitive release of Ca2+ from sarcoplasmic reticulum. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely. inhibitor of voltage-gated sodium channels such as NaV1.4 and NaV1.8. Shown also to reversibly block nicotinic acetylcholine (ACh) receptors (nAChRs).