bs-76875C

DATASHEET

Formulation Solid

Storage: Stable for 2 years after receipt when stored at +4°C.

Product Information:

CAS Number: 93-35-6

Molecular formula: C9H6O3

Molecular weight: 162.14

Purity: >98% (NMR)

Appearance: Beige solid.

Solubility: Soluble in DMSO (10mg/ml), ethanol (5 mg/ml), methanol (5 mg/ml) or dioxane.

InChiKey: ORHBXUUXSCNDEV-UHFFFAOYSA-N

SMILES: O=C1OC2=CC(O)=CC=C2C=C1

SMILES: OC1=CC=C2C=CC(=O)OC2=C1

Description:

Umbelliferone is a naturally occurring derivative and metabolite of coumarin that has diverse biological activities including antitumor, antioxidant, antihyperglycemic, anti-inflammatory, neuroprotective and antidepressant-like properties. It inhibits the growth of a variety of human cell lines. It increases the production of reactive oxygen species (ROS), depolarizes the mitochondrial membrane, and halts the cell cycle at the G0/G1 phase in KB human oral carcinoma cells. Umbelliferone has been used as a ratiometric pH indicator. Spectral Data: Em=460nm / Ex=330(ph<6)/370nm(pH>8). Umbelliferone can also be used as building block to synthesize fluorescent probes or biochemically active APIs.