DATASHEET
Host:
Rabbit
Target Protein:
SLC12A3
Immunogen Range:
951-1021/1021
Clonality:
Polyclonal
Isotype:
IgG
Entrez Gene:
6559
Swiss Prot:
P55017
Source:
KLH conjugated synthetic peptide derived from human SLC12A3
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Background:
Key mediator of sodium and chloride reabsorption in this nephron segment, accounting for a significant fraction of renal sodium reabsorption.
PRODUCT SPECIFIC PUBLICATIONS
- Jayachandran, Muthuvel, et al. "Extracellular vesicles in urine of women with but not without kidney stones manifest patterns similar to men: a case control study." Biol Sex Differ 6.2 (2015).Read more>>
- Turco et al. Specific renal parenchymal-derived urinary extracellular vesicles identify age-associated structural changes in living donor kidneys. (2016) J.Extracell.Vesicle. 5:29642Read more>>
- Chirackal RS et al. Urinary extracellular vesicles associated MCP-1 and NGAL derived from specific nephron segments differ between calcium oxalate stone formers and controls. Am J Physiol Renal Physiol. 2019 Aug 28. Read more>>
- Matsubara, Ai. et al. Low-salt diet increases mRNA expression of aldosterone-regulated transporters in the intermediate portion of the endolymphatic sac. Pflug Arch Eur J Phy. 2022 Feb;:1-11Read more>>
VALIDATION IMAGES
Antigen: bs-7694P, 0.2ug/100ul \nPrimary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000; \nSecondary: HRP conjugated Goat Anti-Rabbit IgG(bs-0295G-HRP) at 1: 5000; \nTMB staining; \nRead the data in MicroplateReader by 450nm. \n