bs-7697R-A555

DATASHEET

Host: Rabbit

Target Protein: Adenovirus 5 E1A binding protein

Immunogen Range: 501-602/602

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 10771

Swiss Prot: Q15326

Source: KLH conjugated synthetic peptide derived from human Adenovirus 5 E1A binding protein

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2) (By similarity). Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth.

Conjugation: ALEXA FLUOR® 555

Excitation/ Emission: 555nm/580nm

Size: 100ul

Concentration: 1ug/ul

Applications: IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 71

Cross Reactive Species: Rat

Predicted Cross Reactive Species: Human
Mouse
Dog
Sheep
Horse
Chicken

For research use only. Not intended for diagnostic or therapeutic use.