bs-7740R-Cy5.5

DATASHEET

Host: Rabbit

Target Protein: CCDC11

Specificity: Due to the similarity of this protein to RWD domain-containing protein 1, there is a chance that this antibody will react with this protein based on a 75% non-sequential amino acid similarity.

Immunogen Range: 331-430/514

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 220136

Swiss Prot: Q96M91

Source: KLH conjugated synthetic peptide derived from human CCDC11

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

CCDC11 is a 514 amino acid protein encode by a gene that maps to human chromosome 18q21.1. Encoding over 300 genes, chromosome 18 contains about 76 million bases. Trisomy 18, or Edwards syndrome, is the second most common trisomy after Downs syndrome. Symptoms of Edwards syndrome include low birth weight, a variety of physical development defects, heart deformations and breathing difficulty. Translocation between chromosome 18 and 14 is the most common translocation in cancers, and occurs in follicular lymphomas. Niemann-Pick disease, hereditary hemorrhagic telangiectasia and erythropoietic protoporphyria are associated with chromosome 18. The TGF modulators, Smad2, Smad4 and Smad7 are encoded by chromosome 18.

Conjugation: Cy5.5

Excitation/ Emission: 675nm/694nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 57

Cross Reactive Species: Human
Mouse
Rat
Others

Predicted Cross Reactive Species: Cow
Horse

For research use only. Not intended for diagnostic or therapeutic use.