bs-82012C

DATASHEET

Formulation Off-White solid

Storage: -20°C

Product Information:

Potent selective inhibitor of Chk2 (IC50 = 15 nM). BML-277 has been screened against a panel of 35 kinases, and shows less that 25% inhibition of any other kinase at 10 µM, demonstrating the selectivity1. Also displays radioprotective activity, preventing apoptosis in human T-cells that were subjected to ionizing radiation (EC50 = 3.0 – 7.6 µM).

Description:

CAS Number: 516480-79-8; Chemical Name: 2-(4-(4-Chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide; Molecular weight: 363.81; Formula: C20H14ClN3O2; Solubility: DMSO (20 mg/ml); Ethanol (20 mg/ml); Physical Properties: Off-white solid; Purity: 98% by TLC [50% ethyl acetate in hexanes; Rf = 0.17] NMR conforms

Size: 5mg, 25mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.