bs-82017C

DATASHEET

Formulation Off-White solid

Storage: -20°C

Product Information:

Potent and specific inhibitor of the protein kinase c-Raf (IC50=70nM). Has no significant effect on many other protein kinases tested (even at 50µM) with the exception of p38 (SAPK2α) (IC50=2µM) and SAPK2β (p38β) (IC50=2µM). Induces a paradoxical >100-fold activation of c-Raf in whole cells. Induces apoptosis in a variety of cell lines. Cell permeable.

Description:

CAS Number: 208260-29-1; Chemical Name: 3-(Dimethylamino)-N-[3-[(4-hydroxybenzoyl)-amino]-4-methylphenyl]benzamide; Molecular weight: 389.46; Formula: C23H23N3O3; Solubility: DMSO (25 mg/ml); Physical Properties: Off-white solid; Purity: 98% by TLC NMR conforms

Size: 5mg, 25mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.