DATASHEET
Formulation
Yellow solid (MP = 223-224°C)
Storage:
-20°C
Product Information:
Inhibits NGF-induced neurite growth in PC12 cells via selective inhibition of NGF receptor(pp140c-trk) autophosphorylation (IC50 = 10 µM). No inhibition of EGF, or PDGF receptor phosphorylation at typical working concentrations.
Description:
CAS Number: 148741-30-4; Chemical Name: 3,5-Di-t-butyl-4-hydroxybenzylidene cyanothioacetamide; Molecular weight: 316.47; Formula: C18H24N2OS; Solubility: DMSO (25 mg/ml) Ethanol (25 mg/ml); Physical Properties: Yellow solid (MP = 223-224°C); Purity: 99% by TLC [5% methanol in methylene chloride, Rf = 0.76] NMR Conforms