DATASHEET
Formulation
White Solid
Storage:
RT
Product Information:
Potent and selective leukocyte elastase inhibitor, IC50 = 44 nM1. Displays no activity at a variety of other proteases. Inhibits NF-κB activation2 and LTB4-induced neutrophil migration in vitro3. Significantly attenuates ischemia-induced spinal cord injury, decreases serum cytokine levels and reduces acute inflammatory lung injury in vivo4.
Description:
CAS Number: 127373-66-4; Chemical Name: N-{2-[({4-[(2,2-Dimethylpropanoyl)oxy]phenyl}sulfonyl)amino]benzoyl}glycine sodium; Molecular weight: 456.45; Formula: C20H21N2O7; Solubility: DMSO (20 mg/ml); Physical Properties: White solid; Purity: 98% by TLC