bs-82082C

DATASHEET

Formulation White Solid

Storage: RT

Product Information:

TRPA1 channel blocker IC50=3.1-4.5 μM in various cell lines. Reduces cinnamaldehyde-induced nociception in vivo and blocks cold- and mustard oil-induced activation of mouse TRPA1 but not capsaicin-induced activation. Does not block TRPV1, V2, V3, V4 or M8 at concentrations up to 50 μM.1 Blocks TRPA1 pore dilation (IC50=10.3 μM).2 An important tool for assessing the role of TRPA1 in cell signaling and physiological processes.3-5

Description:

CAS Number: 55224-94-7; Chemical Name: 4-(4-Chlorophenyl)-3-methylbut-3-en-2-oxime; Molecular weight: 209.67; Formula: C11H12ClNO; Solubility: DMSO (25 mg/ml) Ethanol (25 mg/ml); Physical Properties: White solid; Purity: 98% by TLC [10% Methanol in methylene chloride, Rf = 0.60] NMR Conforms

Size: 10mg, 50mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.