DATASHEET
Formulation
white or off-white solid
Storage:
-20°C
Product Information:
Selectively interacts with HSP70 and disrupts its association with co-chaperones and substrate proteins. Inhibits p53 binding to antiapoptotic proteins Bcl-xL and Bcl-2. Recues primary mouse thymocytes from P53-mediated apoptosis induced by radiation. Cell permeable.
Description:
CAS Number: 64984-31-2; Chemical Name: 2-Phenylethynesulfonamide; Molecular weight: 181.21; Formula: C8H7NO2S; Solubility: DMSO (20 mg/ml) Ethanol (20 mg/ml); Physical Properties: White or off-white solid; Purity: 98% by TLC, NMR (Conforms)