bs-82147C

DATASHEET

Formulation White Solid

Storage: -20°C

Product Information:

Thymidine derivative that acts as an HIV nucleoside reverse transcriptase inhibitor (NRTI) (EC50 = 8.8 nM for HIV-1 replication in human PBMCs).1,2 Down-modulates P2X7-mediated NLRP3 inflammasome activation independent of reverse transcriptase inhibition.3 Reduces production of IL-18 and caspase-1 and stimulates Aβ-induced autophagy in macrophages.4

Description:

CAS Number: 3056-17-5; Chemical Name: 2’,3’-Didehydro-3’-deoxythymidine; Molecular weight: 224.22; Formula: C10H12N2O4; Solubility: DMSO (20 mg/ml) Water (20 mg/ml); Physical Properties: White solid; Purity: >98% by HPLC, NMR (conforms)

Size: 1g, 200mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.