bs-82149C

DATASHEET

Formulation White Solid

Storage: -20°C

Product Information:

5-Fluorouracil (5-FU) is a clinically useful anticancer agent that acts via irreversible inhibition of thymidylate synthase. The active metabolites of 5-FU are 5-Fluorodeoxyuridylate (5-FdUMP), 5-Fluorodeoxyuridine triphosphate (5-FdUTP) and 5-Fluorouridine triphosphate (5-FUTP). The primary cytotoxic effect of 5-FU is believed to be inhibition of thymidylate synthase by 5-FdUMP. Secondary effects include incorporation of 5-FdUTP into DNA resulting in DNA strand breaks and incorporation of 5-FUTP into RNA causing abnormal RNA processing.1

Description:

CAS Number: 51-21-8; Chemical Name: 5-Fluoro-1H,3H-pyrimidine-2,4-dione; Molecular weight: 130.08; Formula: C4H3FN2O2; Solubility: DMSO (25 mg/ml); Physical Properties: White solid; Purity: 98%

Size: 1g, 250mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.