DATASHEET
Formulation
beige solid
Storage:
-20°C
Product Information:
IWP-2 is an inhibitor of Wnt secretion and processing. It blocks Wnt-dependent signaling (IC50=27nM) by inhibition of the O-acyltransferase Porcn1. Induces cardiomyocyte differentiation from human pluripotent stem cells2. An important tool to probe the involvement of the Wnt pathway in physiological processes3,4. Cell permeable.
Description:
CAS Number: 686770-61-6; Chemical Name: N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]-acetamide; Molecular weight: 466.61; Formula: C22H18N4O2S3; Solubility: DMSO (5 mg/ml with warming); Physical Properties: Beige solid; Purity: 98% by TLC, NMR (Conforms)