DATASHEET
Formulation
White Solid
Storage:
RT
Product Information:
A novel inhibitor of the MDM2-p53 interaction. Mimics three p53 residues involved in binding to MDM2. Binds to MDM2 with a Ki of 120 nM. Activates p53 in cancer cells. Cell permeable.
Description:
CAS Number: 6964-62-1; Chemical Name: 2-Methyl-7-[Phenyl(phenylamino)methyl]-8-quinolinol; Molecular weight: 340.43; Formula: C23H20N2O; Solubility: DMSO (25 mg/ml); Physical Properties: White solid; Purity: 97% by TLC / HPLC NMR (Conforms)