bs-82193C
[Life Science]
NSC663284
www.biossusa.com
support@biossusa.com
800.501.7654 [DOMESTIC]
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation Red solid
Storage: -20°C
Product Information:
Potent, selective and irreversible inhibitor of CDC25 phosphatases, Ki=29, 95 and 89 nM for human CDC25A, B2 and C respectively and >20- and >450-fold selective over VHR and PTP1B1. Arrests cells at G1 and G2/M and inhibits cdk1 and 2 activation2. Inhibits the growth of a variety of human tumor cell lines3. Acts via irreversible oxidation of the catalytic cysteine of CDC254.
Description:
CAS Number: 383907-43-5<br></br>Chemical Name: 6-Chloro-7-[[2-(4-morpholinyl)ethyl]amino]-5,8-quinolinedione<br></br>Molecular weight: 321.77<br></br>Formula: C15H16ClN3O3 <br></br>Solubility: DMSO (15 mg/ml) Ethanol (55 mg/ml)<br></br>Physical Properties: Red solid<br></br>Purity: 98% by TLC, NMR (Conforms)
Size: 5mg, 25mg
Applications: Life Science
For research use only. Not intended for diagnostic or therapeutic use.