bs-82193C

DATASHEET

Formulation Red Solid

Storage: -20°C

Product Information:

Potent, selective and irreversible inhibitor of CDC25 phosphatases, Ki=29, 95 and 89 nM for human CDC25A, B2 and C respectively and >20- and >450-fold selective over VHR and PTP1B1. Arrests cells at G1 and G2/M and inhibits cdk1 and 2 activation2. Inhibits the growth of a variety of human tumor cell lines3. Acts via irreversible oxidation of the catalytic cysteine of CDC254.

Description:

CAS Number: 383907-43-5; Chemical Name: 6-Chloro-7-[[2-(4-morpholinyl)ethyl]amino]-5,8-quinolinedione; Molecular weight: 321.77; Formula: C15H16ClN3O3; Solubility: DMSO (15 mg/ml) Ethanol (55 mg/ml); Physical Properties: Red solid; Purity: 98% by TLC, NMR (Conforms)

Size: 5mg, 25mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.