bs-82211C [Life Science]
AG-1517 ยท HCl
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Formulation white or off-white solid

Storage: RT

Product Information:

An ultra-potent inhibitor of epidermal growth factor receptor tyrosine kinase (EGFRK), with an IC50 of 25 pM. Inhibits other tyrosine kinases at micromolar or higher concentrations. It selectively blocks EGF-mediated cellular processes including mitogenesis, early gene expression and oncogenic transformation1. Inhibits the growth of a number of cancer cell lines2. An extremely useful tool for exploring EGF-mediated cellular signaling3.

Description:

CAS Number: 153436-54-5<br></br>Chemical Name: 4-(3-Bromoanilino)-6,7-dimethoxyquinazoline hydrochloride<br></br>Molecular weight: 360.21<br></br>Formula: C16H14BrN3O2<br></br>Solubility: DMSO (5 mg/ml)<br></br>Physical Properties: white or off-white solid<br></br>Purity: 98% by TLC, NMR (Conforms)

Size: 5mg, 25mg

Applications: Life Science

For research use only. Not intended for diagnostic or therapeutic use.