bs-82220C [Life Science]
LYS6K2
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Formulation Yellow solid

Storage: RT

Product Information:

A selective inhibitor of the p70 ribosomal S6 kinase (S6K)1. Blocks the phosphorylation of S6 at concentrations as low as 0.1-0.3 μM with no activity at GSK3β and Erk1/2 at 10 μM2. Useful tool to dissect insulin receptor signaling pathways and was employed to show that the action of mTORC1 on SREB P-1c expression is not mediated by S6K2. Cell permeable.

Description:

CAS Number: 1082949-67-4<br></br>Chemical Name: 4-(4-(4-(4-fluoro-3-(trifluoromethyl)phenyl)-1-methyl-1H-imidazol-2-yl)piperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine<br></br>Molecular weight: 445.42<br></br>Formula: C21H19F4N7<br></br>Solubility: DMSO (1 mg/ml) DMF (3 mg/ml)<br></br>Physical Properties: Yellow solid<br></br>Purity: 97% by HPLC, NMR (conforms)

Size: 5mg, 25mg

Applications: Life Science

For research use only. Not intended for diagnostic or therapeutic use.