bs-82224C [Life Science]
LM22A-4
www.biossusa.com
support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Formulation White solid

Storage: -20°C

Product Information:

Small molecule BDNF mimetic displaying neurotrophhic activity. Partial agonist at TRKB and activates TRKB signaling. In in vitro models of neurodegenerative disease, it prevented neuronal degeneration with equal efficacy to that of BDNF. After in vivo administraton, it caused hippocampal and striatal TrkB activation in mice and improved motor learning after traumatic brain injury in rats1. Improves respiratory function in a mouse models of Rett syndrome2.

Description:

CAS Number: 37988-18-4<br></br>Chemical Name: N,N’N’ Tris(2-hydroxyethyl)-1,3,5-benzenetricarboxamide<br></br>Molecular weight: 339.35<br></br>Formula: C15H21N3O6 <br></br>Solubility: DMSO (50 mg/ml) Water (50 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by TLC, NMR (Conforms)

Size: 5mg, 25mg

Applications: Life Science

For research use only. Not intended for diagnostic or therapeutic use.