DATASHEET
Formulation
White Solid
Storage:
RT
Product Information:
A potent and selective inhibitor of phosphodiesterase PDE11 (IC50=0.28 μM).1 IC50s for PDE1-10 are greater than 100 μM. Restores the ability of p54nrb / NONOKD cells to generate cAMP in response to ACTH stimulation and the production of cortisol and DHEA in response to cAMP signaling.2
Description:
CAS Number: 686770-80-9; Chemical Name: 6,7-Dihydro-3-phenyl-2-(propylthio)thieno[3,2-d]pyrimidin-4(3H)one; Molecular weight: 304.44; Formula: C15H16N2OS2; Solubility: DMSO (50 mg/ml) Ethanol (14 mg/ml with warming); Physical Properties: White solid; Purity: 98% by TLC, NMR (Conforms)