bs-82229C
[Life Science]
Importazole
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation Off-white solid
Storage: RT
Product Information:
Specifically inhibits importin-β-mediated nuclear import without disrupting transportin-mediated nuclear import or CRM1-mediated nuclear export1. When added to cells during mitosis it impairs the release of an importin- cargo probe and causes defects in spindle assembly. Inhibition of importin-β function is most likely mediated by blocking its interaction with RanGTP. It is an important new tool to probe the function of the importin-/RanGTP pathway2-4. Cell permeable
Description:
CAS Number: 662163-81-7<br></br>Chemical Name: N-(1-Phenylethyl)-2-(pyrrolidin-1-yl)quinazolin-4-amine<br></br>Molecular weight: 318.43<br></br>Formula: C20H22N4<br></br>Solubility: DMSO (10 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: 97% by TLC, NMR (Conforms)
Size: 5mg, 25mg
Applications: Life Science
For research use only. Not intended for diagnostic or therapeutic use.