bs-82230C

DATASHEET

Formulation White Solid

Storage: -20°C

Product Information:

Potent and selective ATP citrate lyase (ACL) inhibitor, IC50=0.13 M. Inhibits lipid biosynthesis, IC50=8 M in HepG2 cells.1,2 Reduces weight gain, lowers plasma cholesterol, triglycerides and glucose in high-fat-fed mice.2 A novel tool compound for exploring the potential of ACL inhibition as a target for metabolic disorders such as obesity and dyslipidemia.2 Impairs proliferation or induces death in androgen-depleted castration resistant prostate cancer cells.3 Reduces cell cycle progression in iBN cells.4

Description:

CAS Number: 943962-47-8; Chemical Name: 3,5-Dichloro-2-hydroxy-N-(4-methoxy[1,1’-biphenyl]-3-yl)-benzenesulfonamide; Molecular weight: 424.30; Formula: C19H15Cl2NO4S; Solubility: DMSO (25 mg/ml) Ethanol (20 mg/ml); Physical Properties: White solid; Purity: 98% by TLC NMR (Conforms)

Size: 5mg, 25mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.