bs-82236C
[Life Science]
Gue1654
www.biossusa.com
support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation Off-white solid
Storage: -20°C
Product Information:
Gue1654 is a biased antagonist for the oxoeicosanoid receptor 1 (OXE-R, GPR170)1, the receptor for 5-Oxo-ETE, a proinflammatory eicosanoid2. It selectively inhibits Gβγ but not Gαi signaling upon activation of the Gαi-βγ heterotrimer by OXE-R.1,3 Gue1654 alleviated coronary artery ligation-induced ischemic myocardial injury in a mouse model.4
Description:
CAS Number: 397290-30-1<br></br>Chemical Name: N-[7-(Methylthio)benzo[1,2-d:4,3-d']bisthiazol-2-yl]-α-phenylbenzeneacetamide<br></br>Molecular weight: 447.59<br></br>Formula: C23H17N3OS3<br></br>Solubility: DMSO (40 mg/ml with warming)<br></br>Physical Properties: Off-white solid<br></br>Purity: >98% by TLC, NMR (Conforms)
Size: 5mg,25mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.