DATASHEET
Formulation
White Solid
Storage:
-20°C
Product Information:
A pyrimidine biosynthesis inhibitor and immunomodulator.1 Inhibits the mitochondrial dihydroorotate dehydrogenase (DHODH).2 Leflunomide is rapidly metabolized in human hepatocytes to A77 1726.3 Cell permeable.
Description:
CAS Number: 108605-62-5; Chemical Name: 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-butenamide; Molecular weight: 270.21; Formula: C12H9F3N2O2; Solubility: DMSO (30 mg/ml) Ethanol (5 mg/ml); Physical Properties: White solid; Purity: 98% by TLC, NMR (conforms)