bs-82258C
[Life Science]
Salirasib
www.biossusa.com
support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation White solid
Storage: RT
Product Information:
Salirasib is a synthetic farnesylcysteine mimetic that inhibits ras proteins1,2 via disruption of interactions between the S-Prenyl moiety of Ras and the membrane anchorage domains3. It has been investigated in the treatment of various cancers.4,5 HCC cells pretreated with salirasib were sensitized to TRAIL-induced apoptosis.6 Salirasib has also been shown to inhibit TRPA1 (EC50 = 1.3 µM).7
Description:
CAS Number: 162520-00-5<br></br>Chemical Name: trans-Farnesylthiosalicylic acid<br></br>Molecular weight: 358.54<br></br>Formula: C22H30O2S<br></br>Solubility: DMSO (20 mg/ml) Ethanol (20 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: >98% by TLC NMR (Conforms)
Size: 5mg,25mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.