bs-82258C

DATASHEET

Formulation White Solid

Storage: RT

Product Information:

Salirasib is a synthetic farnesylcysteine mimetic that inhibits ras proteins1,2 via disruption of interactions between the S-Prenyl moiety of Ras and the membrane anchorage domains3. It has been investigated in the treatment of various cancers.4,5 HCC cells pretreated with salirasib were sensitized to TRAIL-induced apoptosis.6 Salirasib has also been shown to inhibit TRPA1 (EC50 = 1.3 µM).7

Description:

CAS Number: 162520-00-5; Chemical Name: trans-Farnesylthiosalicylic acid; Molecular weight: 358.54; Formula: C22H30O2S; Solubility: DMSO (20 mg/ml) Ethanol (20 mg/ml); Physical Properties: White solid; Purity: >98% by TLC NMR (Conforms)

Size: 5mg, 25mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.