bs-82259C
[Life Science]
NSC405020
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation White solid
Storage: RT
Product Information:
Membrane type-1 matrix metalloproteinase (MMP14 or MT1-MMP) inhibitor that prevents homodimerization and inhibits MMP14’s protumorigenic activity in vivo. (IC50 > 100 μM). Inhibition is via interaction with the hemopexin domain (PEX) of MMP14. NSC-405020 does not interfere with the catalytic activity of MT1-MMP or MMP-2. Suppresses bone erosion in a c-Fos-deficient mouse model.2 Decreases arsenic-mediated invasion of human squamous cell carcinoma HSC5 cells.3
Description:
CAS Number: 7497-07-6<br></br>Chemical Name: 3,4-Dichloro-N-(1-methylbutyl)benzamide<br></br>Molecular weight: 260.15<br></br>Formula: C12H15NCl2O<br></br>Solubility: DMSO (25 mg/ml) Ethanol (25 mg/ml)<br></br>Physical Properties: White solid<br></br>Purity: 98% by TLC, NMR (Conforms)
Size: 5mg,25mg
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.