DATASHEET
Formulation
White Solid
Storage:
-20°C
Product Information:
Akt activator. Binds to the pleckstrin homology domain of Akt preventing membrane translocation but paradoxically activating it in the cytosol. Enhances Akt phosphorylation by upstream protein kinases. Suppresses excitotoxicity-induced neuronal death in vitro and in vivo.1 A useful tool for studying the PI3K/Akt axis.2
Description:
CAS Number: 305834-79-1; Chemical Name: 2-Amino-6-chloro-α-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetic acid ethyl ester; Molecular weight: 364.79; Formula: C17H17ClN2O5; Solubility: DMSO (100 mg/ml) Ethanol (40 mg/ml); Physical Properties: White solid; Purity: 98% by TLC, NMR (Conforms)