bs-82268C
[Life Science]
YM-155
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation Tan to yellow solid
Storage: -20°C
Product Information:
A novel small molecule survivin suppressant. YM-155 suppresses expression of survivin (a member of the IAP family) and induced apoptosis in human tumor cell lines at 10 nmol/L with little effect on other IAP or Bcl-2 family members.1 Overcomes erlotinib resistance in EGFR mutation-positive non-small cell lung cancer.2 Induces DNA damage.3 Induces an autophagy-dependent cell death in adenoid cystic carcinoma cells.4
Description:
CAS Number: 781661-94-7<br></br>Chemical Name: 1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazol-3-ium bromide<br></br>Molecular weight: 443.30<br></br>Formula: C20H19BrN4O3<br></br>Solubility: DMSO (25 mg/ml)<br></br>Physical Properties: Tan to yellow solid<br></br>Purity: >98% by TLC NMR (Conforms)
Size: 5mg, 25mg
Applications: Life Science
For research use only. Not intended for diagnostic or therapeutic use.