bs-82281C

DATASHEET

Formulation White or slightly yellow solid

Storage: RT

Product Information:

Selective ALK5 inhibitor, IC50 = 59, 400 and 1400 nM for TGF-β RI, TGF-β RII and MLK-7K, respectively1. Inhibits Smad2 phosphorylation induced by TGF-β as well as fibronectin expression and MDA-MB-231 cell invasion2. Abolishes resistance of glioblastoma-initiating cells to radiation3. Cell permeable.

Description:

CAS Number: 396129-53-6; Chemical Name: 4-(3-Pyridin-2-yl-1H-pyrazol-4-yl)quinolone; Molecular weight: 272.31; Formula: C17H12N4; Solubility: DMSO (25 mg/ml); Physical Properties: Beige solid; Purity: 98% by TLC

Size: 25mg, 5mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.