DATASHEET
Formulation
Brown solid
Storage:
-20°C
Product Information:
Selective protein arginine methyltransferase 1 (PRMT1) inhibitor, IC50 = 1.5 μM. Displays no activity against CARM1 and Set7/9 methyltransferases. Inhibits growth of MCF7a breast cancer cells and LNCaP prostate cancer cells. Blocks androgen-induced gene expression in LNCaP cells1.
Description:
CAS Number: 17328-16-4; Chemical Name: N,N’-(Sulfonyldi-4,1-phenylene)bis(2-chloroacetamide); Molecular weight: 401.26; Formula: C16H14Cl2N2O4S; Solubility: DMSO 50 mg/ml; Physical Properties: Brown solid; Purity: 98% by HPLC NMR (Conforms)