bs-82296C

DATASHEET

Formulation yellow solid

Storage: -20°C

Product Information:

A selective, cell-permeable non-peptide calpain inhibitor (Ki for μ- and m-calpains = 0.21 and 0.37 μM respectively). Acts at the calcium binding site of calpain rather than the substrate-binding site. Inhibits calpain activity in two intact cell systems. Attenuates hypoxic/hypoglycemic injury to cerebrocortical neurons in culture and excitotoxic injury to Purkinje cells in cerebellar slices1. Displays cytoprotective effects in oxidant- and calcium ionophore-induced cell death2. Some protective effects may be due to inhibition of MMP activity3.

Description:

CAS Number: 179528-45-1; Chemical Name: (Z)-3-(4-Iodophenyl)-2-mercapto-2-propenoic acid; Molecular weight: 306.12; Formula: C9H7IO2S; Solubility: DMSO (30 mg/ml) Ethanol (15 mg/ml); Physical Properties: Yellow solid; Purity: 98% by TLC, NMR (Conforms)

Size: 5mg, 25mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.