bs-82308C

DATASHEET

Formulation Brown waxy solid

Storage: -20°C

Product Information:

A GPR40 receptor antagonist1. Suppresses fatty acid-induced elevation of intracellular Ca++. Inhibits palmitic acid potentiated glucose–stimulated insulin secretion in Min6 pancreatic β cells in vitro. Lowers serum insulin levels, increases insulin sensitivity2 in obese Zucker rats (6 mg/kg)2. Reduces pancreatic β cell apoptosis in obese diabetic (db/db) rats3. Protects Min6 β cells from palmitic acid-induced ER stress and apoptosis4

Description:

CAS Number: 346692-04-4; Chemical Name: N-(4-Butylphenyl)-4-fluorobenzenesulfonamide; Molecular weight: 307.37; Formula: C16H18NO2S; Solubility: DMSO (80 mg/ml) Ethanol (80 mg/ml); Physical Properties: Brown waxy solid; Purity: 98% by HPLC NMR (Conforms)

Size: 5mg, 25mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.