DATASHEET
Formulation
White Solid
Storage:
-20°C
Product Information:
DiMNF is a selective aryl hydrocarbon receptor (AHR) modulator (SAhRM). It exhibits antiinflammatory activity including suppression of cytokine-mediated acute phase genes through dissociation of non-dioxin-response element (DRE) AHR activity from DRE-dependent xenobiotic gene expression1. Represses the cytokine-mediated induction of CD55 and therefore may have therapeutic potential in regulating the immune response to tumor formation2. Represses estrogen-inducible transcription3.
Description:
CAS Number: 14756-24-2; Chemical Name: 2-(3,2-Dimethoxyphenyl)-4H-naphtho[1,2-b]pyran-4-one; Molecular weight: 332.45; Formula: C21H16O4; Solubility: DMSO (1.5 mg/ml); Physical Properties: White solid; Purity: 99% by HPLC NMR (Conforms)