bs-82322C [Life Science]
Ro 31-8425 HCl
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Formulation Red Solid

Storage: -20°C

Product Information:

Selective, reversible, ATP-competitive inhibitor of protein kinase C. Inhibits PKCα, β1, β2, γ and ε, IC50= 8, 8, 14,13 and 39 nM respectively.1 Extremely useful tool for probing PKC-dependent physiology2 or signaling pathways3. Increases MSC adhesion to an ICAM-1 coated substrate in vitro and enables targeted delivery of systematically administered MSCs to inflamed sites in vivo in a CD11a-dependent manner.4 Cell permeable.

Description:

CAS Number: 145317-11-9; Chemical Name: 3-[8-(Aminomethyl)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methylindol-3-yl)pyrrol-2,5-dione hydrochloride; Molecular weight: 460.96; Formula: C26H24N4O2 · HCl; Solubility: DMSO (10 mg/ml); Physical Properties: Red solid; Purity: 98% by TLC, NMR (Conforms)

Size: 5mg, 1mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.