bs-82385C

DATASHEET

Formulation Off-White solid

Storage: -20°C

Product Information:

Myriocin is a fungal metabolite with potent immunosuppressant activity.1 It inhibits serine palmitoyltransferase (Ki = 0.28 nM) blocking the synthesis of ceramide.2 It was found to suppress melanoma cell proliferation by cell cycle arrest at the G 2/M phase through decreased sphingolipid levels and increased p53 and p21 (waf1/cip1) expression.3

Description:

CAS Number: 35891-70-4; Chemical Name: (2S,3R,4R,6E)-2-Amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic acid; Molecular weight: 401.54; Formula: C21H39NO6; Solubility: DMSO (20 mg/ml); Physical Properties: Off-white solid; Purity: >98%

Size: 5mg, 25mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.