bs-82403C
[Life Science]
Doramapimod
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation White or off-white solid
Storage: -20°C
Product Information:
Potently and selectively inhibits p38 MAPK by simultaneously binding to the ATP-binding domain and an allosteric site.1 (IC50=18 nM). Displays anti-inflammatory activity2 but differential effects on inflammatory genes3. Cell permeable.
Description:
CAS Number: 285983-48-4<br></br>Chemical Name: 1-[5-tert-Butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[4-(2-morpholin-4-ylethoxy)naphthalene-1-yl]urea<br></br>Molecular weight: 527.66<br></br>Formula: C31H37N5O3<br></br>Solubility: DMSO (50 mg/ml) Ethanol (30 mg/ml)<br></br>Physical Properties: White or off-white solid<br></br>Purity: 98% by TLC, NMR (Conforms)
Size: 5mg, 25mg
Applications: Life Science
For research use only. Not intended for diagnostic or therapeutic use.