bs-82403C [Life Science]
Doramapimod
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Formulation white or off-white solid

Storage: -20°C

Product Information:

Potently and selectively inhibits p38 MAPK by simultaneously binding to the ATP-binding domain and an allosteric site.1 (IC50=18 nM). Displays anti-inflammatory activity2 but differential effects on inflammatory genes3. Cell permeable.

Description:

CAS Number: 285983-48-4; Chemical Name: 1-[5-tert-Butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[4-(2-morpholin-4-ylethoxy)naphthalene-1-yl]urea; Molecular weight: 527.66; Formula: C31H37N5O3; Solubility: DMSO (50 mg/ml) Ethanol (30 mg/ml); Physical Properties: White or off-white solid; Purity: 98% by TLC, NMR (Conforms)

Size: 5mg, 25mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.