bs-82407C
[Life Science]
Erlotinib · HCl
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support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation White or off-white solid
Storage: -20°C
Product Information:
Potent inhibitor of EGFR tyrosine kinase (IC50 = 2 nM)1. Potent inhibitor of mutant JAK2-V617F2. Weaker inhibitor of ErbB-2 kinase (Ki = 1 μM) ErbB-4 kinase (Ki = 1.5 μM)3. HDAC inhibitors sensitize for erlotinib activity in EGFR-mutated and wildtype non-small cell lung cancer (NSCLC) cells4. A clinically effective agent for NSCLC5.
Description:
CAS Number: 183319-69-9<br></br>Chemical Name: N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine hydrochloride<br></br>Molecular weight: 429.91<br></br>Formula: C22H23N3O4 · HCl<br></br>Solubility: DMSO (18 mg/ml)<br></br>Physical Properties: White or off-white solid<br></br>Purity: 98% by TLC, NMR (Conforms)
Size: 10mg, 100mg
Applications: Life Science
For research use only. Not intended for diagnostic or therapeutic use.