DATASHEET
Formulation
Off-White solid
Storage:
-20°C
Product Information:
A potent inhibitor of class I and II HDACs1. Cotreatment with panobinostat and an HSP90 inhibitor caused synergistic apoptosis in human CML-BC and AML cells2. A potent antimyeloma agent that overcomes drug resistance3.
Description:
CAS Number: 404950-80-7; Chemical Name: (E)-N-Hydroxy-3-(4-((2-(2-methyl-1H-indol-3-yl)ethylamino)methyl)phenyl)acrylamide; Molecular weight: 349.44; Formula: C21H23N3O2; Solubility: DMSO (100 mg/ml) Ethanol (5 mg/ml); Physical Properties: Off-white solid; Purity: 98% by TLC, NMR (Conforms)