bs-82486C

DATASHEET

Formulation White Solid

Storage: -20°C

Product Information:

Potent and selective PARP-inhibitor with Ki values of 5.2 nM and 2.9 nM for PARP-1 and PARP-2, respectively.1 Restores sensitivity to DNA alkylator/methylator temozolomide in glioma cells and xenografts2, and enhances radiotherapy sensitivity in endometrial carcinoma cells3. Also improves sensitivity to DNA replication inhibitor cisplatin in human oral carcinoma cells.4

Description:

CAS Number: 912445-05-7; Chemical Name: 2-[(2R)-2-Methyl-2-pyrrolidinyl]-1H-benzimidazole-7-carboxamide dihydrochloride; Molecular weight: 317.22; Formula: C13H16N4O·2HCl; Solubility: DMSO (30 mg/ml) Water (40 mg/ml); Physical Properties: White solid; Purity: 98% by TLC, NMR (Conforms)

Size: 5mg, 25mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.