DATASHEET
Formulation
Yellow solid
Storage:
RT
Product Information:
Potent and selective ALK4, ALK5 and ALK7 inhibitor (TGFβ superfamily Type I activin receptor-like kinase). (ALK5 IC50 = 94 nM)1,2. Inhibits TGFβ-induced proliferation of human osteosarcoma cells3. Ehances growth and integrity of embryonic stem cell-derived endothelial cells4. A frequently used agent employed in numerous stem cell differentiation protocols5. Cell permeable.
Description:
CAS Number: 301836-41-9<br></br>Chemical Name: 4-[4-(1,3-Benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide<br></br>Molecular weight: 384.40<br></br>Formula: C22H16N4O3<br></br>Solubility: DMSO (30 mg/ml) Ethanol (3 mg/ml)<br></br>Physical Properties: Yellow solid<br></br>Purity: 99% by HPLC NMR (Conforms)