bs-82511C
[Life Science]
TTNPB
www.biossusa.com
support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET
Formulation Off-white solid
Storage: -20°C
Product Information:
Highly potent and selective retinoic acid analog acting as an RAR agonist (EC50 = 21, 4 and 2.4 nM for RARα, RARβ and RARγ respectively).1 TTNPB has been extensively used in stem cell differentiation protocols. It enhances reprogramming efficiency in chemically induced pluripotent stem cells.2 Chondrocytes are robustly induced from human pluripotent stem cells by treatment with CHIR99021 and TTNPB.3 TTNPB alone, efficiently converts primary adult mouse fibroblasts into dermal papilla cell-like cells.4 Can be used in combination with other small molecules for induction of mouse totipotent stem cells.5
Description:
CAS Number: 71441-28-6<br></br>Chemical Name: 4-[(E)-2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl]benzoic acid<br></br>Molecular weight: 348.49<br></br>Formula: C24H28O3<br></br>Solubility: DMSO (4 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: >98% by HPLC, NMR (Conforms)
Size: 25mg, 5mg
Applications: Life Science
For research use only. Not intended for diagnostic or therapeutic use.