DATASHEET
Formulation
yellow solid
Storage:
-20°C
Product Information:
Potent inhibitor of HMG-CoA reductase, IC50=40-100 nM.1 Clinically useful, orally active antihypercholesterolemic agent. Inhibits vascular smooth muscle proliferation, IC50=70 nM.2 Displays antineuroinflammatory activity.3 Prevents lung adenocarcinoma bone metastasis by triggering autophagy.4 Attenuates cell proliferation in hepatocellular carcinoma.5
Description:
CAS Number: 93957-55-2; Chemical Name: (+/-)(3R*,5S*,6E)-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid sodium salt; Molecular weight: 466.45; Formula: C24H25FNO4 Na; Solubility: DMSO (40 mg/ml) Water (10 mg/ml); Physical Properties: Yellow solid; Purity: 98% by HPLC NMR (Conforms)