DATASHEET
Formulation
Red Solid
Storage:
-20°C
Product Information:
Potent and selective inhibitor of PI 3-kinase (PI 3-K ), IC50 = 8 nM displaying 30-fold selectivity over PI 3-K and PI 3-K and 7.5-fold selectivity over PI 3-K1. Suppresses joint inflammation in two distinct mouse models1. Ameliorates surgical brain injury2, colitis3, intimal hyperplasia-induced inflammatory processes4 and renal injury/fibrosis5 in rodent models. Orally active.
Description:
CAS Number: 648450-29-7; Chemical Name: 5-(6-Quinoxalinylmethylene)-2,4-thiazolidine-2,4-dione; Molecular weight: 257.27; Formula: C12H7N3O2S; Solubility: DMSO (1.5 mg/ml); Physical Properties: Red solid; Purity: 98% by TLC NMR (Conforms)