bs-82541C [Life Science]
Monastrol
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Formulation Beige solid

Storage: -20°C

Product Information:

Potent, cell-permeable, small molecule inhibitor of mitosis. Monastrol-arrested cells are characterized by monopolar spindles.1 Does not affect other motor proteins or tubulin. Specifically inhibits the mitotic molecular motor kinesin Eg5, a motor protein required for spindle formation (IC50 = 14 μM).2 Mimics the effect of amyloid β on long term potentiation in a cellular model of learning and memory.3 Enhances regeneration of adult axons.4

Description:

CAS Number: 254753-54-3<br></br>Chemical Name: 1,2,3,4-tetrahydro-4-(3-hydroxyphenyl)-6-methyl-2-thioxo-5-pyrimidinecarboxylic acid, ethyl ester<br></br>Molecular weight: 292.35<br></br>Formula: C14H16N2O3S<br></br>Solubility: DMSO (25 mg/ml) Ethanol (25 mg/ml)<br></br>Physical Properties: Beige solid<br></br>Purity: 98% by TLC NMR (Conforms)

Size: 5mg,25mg

Applications: Life Science()

For research use only. Not intended for diagnostic or therapeutic use.