bs-82547C

DATASHEET

Formulation Purple solid

Storage: -20°C

Product Information:

A novel Bcl-2 homology domain-3 (BH3) mimetic1. Inhibits primary acute myeloid leukemia (AML) progenitor cell proliferation (IC50=0.18 μM) and induces apoptosis in primary AML cells (IC50= 3.6 μM)2. Synergizes with other agents such as chloroquine3 and cytarabine4 in cytotoxicity against a variety of cancer cells.

Description:

CAS Number: 803712-79-0; Chemical Name: 2-[2-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-3-methoxy-2H-pyrrol-5-yl]-1H-indole methanesulfonate; Molecular weight: 413.50; Formula: C20H19N3O · CH3SO3H; Solubility: DMSO (5 mg/ml); Physical Properties: Purple solid; Purity: 98% by TLC

Size: 5mg, 25mg

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.