bs-82559C

DATASHEET

Formulation Off-White solid

Storage: -20°C

Product Information:

Indole alkaloid isolated from Rauwolfia serpentina which acts as a potent antihypertensive agent. Irreversibly inhibits both isoforms of vesicular monoamine transporter VMAT1 and 2, Ki=34 and 12 nM, respectively.1,2 May be used to pharmacologically deplete monoamines in various animal models.3 Inhibits the multidrug resistance protein P-glycoprotein, IC50=0.5 mM.3 Reserpine-induced hypokinesia is considered a useful animal model of Parkinson’s disease.5

Description:

CAS Number: 50-55-5; Chemical Name: (3β,16β,17α,18β,20α)-11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-yohimban-16-carboxylic acid, methyl ester; Molecular weight: 608.68; Formula: C33H40N2O9; Solubility: DMSO (35 mg/ml); Physical Properties: Off-white solid; Purity: 98% by TLC NMR (Conforms)

Size: 1g

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.