bs-82559C [Life Science]
Reserpine
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Formulation Off-white solid

Storage: -20°C

Product Information:

Indole alkaloid isolated from Rauwolfia serpentina which acts as a potent antihypertensive agent. Irreversibly inhibits both isoforms of vesicular monoamine transporter VMAT1 and 2, Ki=34 and 12 nM, respectively.1,2 May be used to pharmacologically deplete monoamines in various animal models.3 Inhibits the multidrug resistance protein P-glycoprotein, IC50=0.5 mM.3 Reserpine-induced hypokinesia is considered a useful animal model of Parkinson’s disease.5

Description:

CAS Number: 50-55-5<br></br>Chemical Name: (3β,16β,17α,18β,20α)-11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-yohimban-16-carboxylic acid, methyl ester<br></br>Molecular weight: 608.68<br></br>Formula: C33H40N2O9<br></br>Solubility: DMSO (35 mg/ml)<br></br>Physical Properties: Off-white solid<br></br>Purity: 98% by TLC NMR (Conforms)

Size: 1g

Applications: Life Science()

For research use only. Not intended for diagnostic or therapeutic use.