bs-82569C

DATASHEET

Formulation solid

Storage: -20°C

Product Information:

A potent, cell-permeable Epac (exchange protein directly activated by cAMP) activator1. Induces RAP1 activation and insulin secretion in pancreatic beta cell lines2-5. Induces vascular relaxation in rat mesenteric artery6. The acetoxymethyl ester confers increased cell-permeability and is cleaved by endogenous esterases to yield the active compound, 8-pCPT-2'-O-Me-cAMP. Addition to cell cultures should be done in serum-free media as esterases in serum will cleave the acetoxymethyl ester and reduce cell permeability.

Description:

CAS Number: 1152197-23-3; Chemical Name: 8-(4-Chlorophenylthio)-2’-O-methyladenosine-3’,5’-cyclic monophosphate, acetoxymethyl ester; Molecular weight: 557.91; Formula: C20H21ClN5O8PS; Solubility: DMSO (50 mg/ml); Physical Properties: solid; Purity: 97% by HPLC

Size: 100ug

Applications: Life Science(N/A)

For research use only. Not intended for diagnostic or therapeutic use.